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Akron Children's > Research Institute > Research Studies > Search Clinical Studies

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Matching Clinical Studies

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A study evaluating the safety and efficacy of Debio 4326 in treating precocious puberty in children receiving gonadotropin-releasing hormone agonist

A Study to Assess the Efficacy, Safety and Pharmacokinetics of Debio 4326 in Pediatric Participants Receiving Gonadotropin-Releasing Hormone Agonist Therapy for Central Precocious Puberty (LIBELULA)

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Currently recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

ACNS1831: A Phase 3 Randomized Study of Selumetinib (IND # 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)

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Currently recruiting

A study of treatment for medulloblastoma using sodium thiosulfate to prevent hearing loss

ACNS2031: A Phase 3 Study of Sodium Thiosulfate for the Reduction of Cisplatin-Induced Ototoxicity in Children with Average-Risk Medulloblastoma and Reduced Therapy for Children with Medulloblastoma with Low-Risk Features

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Currently recruiting

A Study to Assess Children with Hypochondroplasia

A Multicenter Multinational Observational Study of Children with Hypochondroplasia

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Currently recruiting

A study to compare standard therapy to treat Hodgkin Lymphoma with the use of two drugs, Brentuximab Vedotin and Nivolumab

AHOD2131: A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma

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Currently recruiting

A study to compare treatment with Selumetinib alone vs. Selumetinib and Vinblastine in patients with recurrent or progressive low-grade glioma

A Study to Compare Treatment with Selumetinib alone vs. Selumetinib and Vinblastine in patients with recurrent or progressive low-grade glioma

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Currently recruiting

A study to give treatment inside the eye to treat retinoblastoma

ARET2121: Intravitreal Melphalan for Intraocular Retinoblastoma

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Currently recruiting

A study to test the addition of the drug Cabozantinib to chemotherapy in patients with newly diagnosed osteosarcoma

AOST2032: A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

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Currently recruiting

A study using risk factors to determine treatment for children with favorable histology Wilms tumors (FHWT)

AREN2231: Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT)

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Currently recruiting

Accelerated v’s standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours (P3BEP)

AGCT1532 - P3BEP Trial, Phase 3 Accelerated BEP Trial: A randomized phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumors.

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Currently recruiting

Active surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in treating pediatric and adult patients with germ cell tumors

AGCT1531, A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors

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Currently recruiting

Alpers Huttenlocher natural history study (Alpers)

Alpers Huttenlocher Natural History Study (Alpers)

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Currently recruiting

An assessment of clinical efficacy of hypothermic therapy following Pivotal Trial II (mTBI) in the adolescent athlete with concussion

An assessment of clinical efficacy of hypothermic therapy following Pivotal Trial II (mTBI) in the adolescent athlete as compared to an untreated active control population

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Currently recruiting

Bracing vs casting in the treatment of idiopathic early-onset scoliosis

Bracing vs Casting in the Treatment of Idiopathic Early-Onset Scoliosis

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Currently recruiting

Chemotherapy for the treatment of patients with newly-diagnosed very low risk and low risk fusion negative rhabdomyosarcoma

ARST2032: A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma

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Currently recruiting

Dinutuximab with chemotherapy, surgery and stem cell transplantation for the treatment of children with newly-diagnosed high risk neuroblastoma

ANBL2131: A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma

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Currently recruiting

Dupixent in post-burn pruritus

A Phase 2 Double-Blind, Randomized, Placebo-Controlled Study to Assess the Efficacy of Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic

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Currently recruiting

Effects of Dexrazoxane Hydrochloride on biomarkers associated with cardiomyopathy and heart failure

ALTE11C2: Health Effects After Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-Related Cardiomyopathy

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Currently recruiting

Efficacy of KL1333 in adult patients with primary mitochondrial disease

An interventional, randomised, double-blind, parallel-group, placebo-controlled, flexible-dose, adaptive study of the efficacy of KL1333 in adult patients with primary mitochondrial disease

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Currently recruiting

Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

ANBL1232: Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients With Non-high-risk Neuroblastoma

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Currently recruiting

IBD ImproveCareNow Registry - working to improve the care and health of children with inflammatory bowel disease

Using patient data to transform care and improve outcomes for children, adolescents, and young adults with Inflammatory Bowel Disease --- ImproveCareNow Database

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Currently recruiting

Implementation of a US/Canadian Diagnostic Registry of Children with Chronic Vasculitis

ARCHIVE (A Registry for Children with Vasculitis: e-entry) Implementation of a US/Canadian Diagnostic Registry of Children with Chronic Vasculitis

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Currently recruiting

Maintenance Chemotherapy or Observation Following Induction Chemo and Radiation for Ependymoma

Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients With Newly Diagnosed Ependymoma Ages 1 to 21 Years

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Currently recruiting

Medical device study for patients with a rare kidney disease (Focal Segmental Glomerulosclerosis)

Treatment of Drug-Resistant Pediatric Focal Segmental Glomerulosclerosis Using the Liposorber ® LA-15 System

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Currently recruiting

Nivolumab in combination with chemo-immunotherapy for the treatment of newly diagnosed primary mediastinal B-Cell lymphoma

ANHL1931: A Randomized Phase 3 trial of Nivolumab(NSC# 748726 IND# 125462) in Combination with Chemo-immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-cell Lymphoma

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Currently recruiting

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

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Currently recruiting


Currently recruiting

Prospective Database Registry of Scheuermann's Kyphosis

Prospective Database Registry of Scheuermann's Kyphosis

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Currently recruiting

Prospective Database Registry of Scoliosis in Children with Cerebral Palsy

Prospective Database Registry Study of Scoliosis in Children with Cerebral Palsy

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Currently recruiting

Recovery after ECMO in children with Acute Respiratory Distress Syndrome

ASCEND (ARDS in Children and ECMO initiation strategies impact on Neuro-Development)

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Currently recruiting

ROCK Prospective Cohort Study for Osteochondritis Dissecans of the Knee

ROCK Comprehensive Prospective Cohort for Osteochondritis Dissecans of the Knee

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Currently recruiting

Safety and efficacy of MACI in Patients with Chondral or Osteochondral Knee Defects (PEAK)

A prospective, open-label, randomized, concurrent active-controlled, longitudinal, multicenter, phase 3 clinical study of the safety and efficacy of MACI in patients aged 10 to 17 years with symptomatic chondral or osteochondral defects of the knee due to osteochondritis dissecans or acute trauma (PEAK Clinical Trial)

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Currently recruiting

Safety and Efficacy of Nexium in Pediatric Patients with Erosive Esophagitis

A Phase III Study to Assess the Efficacy and Safety of NEXIUM for Maintenance of Healing of Erosive Esophagitis in Pediatric Patients 1 to 11 Years of Age

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Currently recruiting

Safety and efficacy of Ravulizumab for pediatric patients with thrombocytic microangiopathy following hematopoetic stem cell transplantation

ALXN1210-TMA-314: A Phase 3, Open-label, Single Arm, Multicenter Study of Ravulizumab in Addition to Best Supportive Care in Pediatric Participants (from 1 month to < 18 years of age) with Thrombotic Microangiopathy (TMA) after Hematopoietic Stem Cell Transplantation (HSCT)

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Currently recruiting

Safety and efficacy of Rimegepant for the treatment of migraine in pediatric patients ≥6 to <18 years of age

Phase 3, multicenter, randomized, double-blind, group sequential, placebo-controlled study to assess efficacy and safety of rimegepant for the treatment of migraine (with or without aura) in children and adolescents ≥ 6 to <18 years of age

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Currently recruiting

Safety and Efficacy of Subdermal Betadine During Posterior Spinal Fusion

Subdermal Betadine to Reduce Microbacterial Bioburden During Posterior Spinal Fusion

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Currently recruiting

Scoliosis Outcomes Database Registry

Scoliosis Outcomes Database Registry

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Currently recruiting

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

A Phase 1 and Phase II and Re-Treatment Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma

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Currently recruiting

Selumetinib vs. Carboplatin and Vincristine in patients with low-grade glioma

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

More about this study...


Currently recruiting

STOP 360: Standardizing Treatments for Pulmonary Exacerbations: A platform for evaluating treatment decisions to improve outcomes

Standardizing Treatments for Pulmonary Exacerbations: A platform for evaluating treatment decisions to improve outcomes

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Currently recruiting

Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

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Currently recruiting

Study of Scoliosis Correction in patients with Marfan Syndrome

Study of Scoliosis Correction in Marfan Syndrome Patients

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Currently recruiting

Study to determine the safety and tolerability of SNDX-5613 in patients with relapsed/refractory leukemia

AALL2121-A Phase 2 study of SNDX-5613 in combination with chemotherapy for patients with relapsed or refractory KMT2A-rearranged infant leukemia

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Currently recruiting

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

ACCL1931: Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

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Currently recruiting

The CARRA Registry for Pediatric Rheumatic Diseases

Observational Study Of Pediatric Rheumatic Diseases: The CARRA Registry

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Currently recruiting

The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

APEC14B1 - The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

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Currently recruiting

Thoracotomy versus thoracoscopic management of pulmonary metastases in patients with osteosarcoma

AOST2031: A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients with Osteosarcoma

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Currently recruiting

Treatment of newly-diagnosed diffuse anaplastic Wilms tumors (SAWT) and relapsed favorable histology Wilms tumors (FHWT)

AREN1921: Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT)

More about this study...


No longer recruiting

TrialNet Pathway to Prevention of T1D

Pathway to Prevention Study Protocol TN-01

More about this study...


Currently recruiting

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