Matching Clinical Studies

A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL

For complete study information, please visit clinicaltrials.gov.

A Registry for Adult and Pediatric Idiopathic Thrombocytopenic Purpura (ITP)

Pediatric and Adult Intercontinental Registry on Idiopathic Thrombocytopenic Purpura (ITP)

A study for relatives of people with type 1 diabetes

Natural History Study of the Development of Type 1 Diabetes

A study testing the BrainPort® artificial vision system

Continued study of Artificial Vision: Evaluation of the BrainPort® System and Investigation of Visual Ambulation

ACNS02B3, A Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens

For complete information, please view the study on clinicaltrials.gov

Alpers Huttenlocher Natural History Study (Alpers)

Alpers Huttenlocher Natural History Study (Alpers)

Apixaban for Prevention of Blood Clots in Children With Leukemia

A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Pegylated (PEG) L-Asparaginase

Assessment of reachable workspace in patients undergoing elbow or shoulder surgery

Reachable Workspace to Assess Upper Extremity Function and Outcomes

Assessment of reachable workspace in patients with Brachial Plexus (BP) or Cerebral Palsy (CP)

Reachable Workspace to Assess Function in Patients with Brachial Plexus Birth Injuries or Cerebral Palsy

Biomarkers in Tumor Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

ANBL00B1 Neuroblastoma Biology Studies

Building Evidence for Effective Palliative/End of Life Care for Teens With Cancer (FACE-TC)

Building Evidence for Effective Palliative/End-of-Life Care for Teens with Cancer (FACE-TC)

Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Hodgkin Lymphoma

A Randomized Phase III Study of Brentuximab Vedotin (SGN-35) for Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents

Community Counts - The Registry for Bleeding Disorders Surveillance

CDC Public Health Surveillance Project (CDC PHSP) for Bleeding Disorders, Mortality Reporting and The Registry for Bleeding Disorder Surveillance

Comparing silver nitrate application with topical corticosteroids at gastrostomy sites

Randomized clinical trial comparing silver nitrate application with topical corticosteroids for hyper-granulation tissue at gastrostomy sites

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Phase II Study of Denosumab (NSC# 744010), a RANK Ligand Antibody, for Recurrent or Refractory Osteosarcoma

Effectiveness of Ribociclib Following Radiation in Children with Diffuse Pontine Gliomas

CLEE011XUS17T: A Phase I/II Study of Ribociclib, a CDK4/6 Inhibitor, Following Radiation Therapy in Children with Newly-diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High-grade Gliomas (HGG)

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure

ALTE11C2: Health Effects After Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-Related Cardiomyopathy

Efficacy and Safety of SAGE-547 Injection in the Treatment of Subjects With Super-Refractory Status

For complete study information, please visit clinicaltrials.gov.

Efficacy of Carboplatin Administered With Radiation and Isotretinoin for Medulloblastoma

For complete study information, please visit clinicaltrials.gov.

Efficacy of KL1333 in adult patients with primary mitochondrial disease

An interventional, randomised, double-blind, parallel-group, placebo-controlled, flexible-dose, adaptive study of the efficacy of KL1333 in adult patients with primary mitochondrial disease

Enrollment on the Childhood Cancer Research Network

Protocol for the Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) Children s Oncology Group

Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

ADVL1513: A Phase 1 Study of Entinostat, an Oral Histone Deacetylase Inhibitor, in Pediatric Patients With Recurrent or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Evaluating the pharmacokinetics of understudied drugs in children

Pharmacokinetics of Understudied Drugs Administered to Children per Standard of Care

Evaluating the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis

A Phase 2, Randomized, Double‑blind, Controlled Study to Evaluate the Safety of VX‑152 Combination Therapy in Adults With Cystic Fibrosis Protocol: VX16-152-102

Evaluation of a Cooling Therapy following Concussion in Adolescent Athletes

An assessment of clinical efficacy of hypothermic therapy immediately following mild traumatic brain injury (mTBI) in the adolescent athlete as compared to an untreated active control population

Family Bereavement within Akron Children's Hospital

Family Bereavement within Akron Children's Hospital Study

Ferimoxytol vs. Iron Sucrose in Pediatric Anemia Patients

A Phase 3, Randomized, Open-Label, Multicenter Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects with Chronic Kidney Disease Protocol No: AMAG-FER-CKD-354

Follow-Up Study Of Tofacitinib For Treatment Of Juvenile Idiopathic Arthritis (JIA)

Please visit clinicaltrials.gov for complete study information.

Genes that influence the way your body responds to infection

Genomic Analysis of Pediatric Systemic Inflammatory Response Syndrome (SIRS) and The Pediatric Sepsis Biomarker Risk Model (PERSEVERE)

Genetic Analysis Identifying Late Occurring Complications in Childhood Cancer Survivors (ALTE03N1)

ALTE03N1: Key Adverse Events After Childhood Cancer

Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

ANBL1232: Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients With Non-high-risk Neuroblastoma

How children and adults with mitochondrial myopathy respond to exercise

Physiological manifestations of exercise intolerance in children (and adults) with mitochondrial myopathies

Implementation of a US/Canadian Diagnostic Registry of Children with Chronic Vasculitis

ARCHIVE (A Registry for Children with Vasculitis: e-entry) Implementation of a US/Canadian Diagnostic Registry of Children with Chronic Vasculitis

Incidence of and Risk Factors for Fibrosing Colonopathy in Patients With Cystic Fibrosis

A Long-Term Prospective Observational Safety Study of the Incidence of and Risk Factors for Fibrosing Colonopathy in US Patients With Cystic Fibrosis Treated With Pancreatic Enzyme Replacement Therapy: A Harmonized Protocol Across Sponsors

Indirect Intracranial Pressure Measurement in Patients With Suspected or Documented Concussion

Indirect Intracranial Pressure Measurement in Patients With Suspected or Documented Concussion

Inhibitor Concurrent with Radiation Therapy for the Treatment of Children with Gliomas

A Phase 1 Study of AZD1775 (MK-1775) Concurrent With Local Radiation Therapy for the Treatment of Newly Diagnosed Children With Diffuse Intrinsic Pontine Gliomas

Innovative Management Strategies for Pediatric Pneumonia in Ohio -- CHIRP

Worldwide, pneumonia is the leading cause of death in children under five years of age. Akron Children's Hospital is one of six pediatric hospitals in Ohio, all members of the Ohio Children's Hospitals Association and the Children's Hospitals' Initiative for Research in Pneumonia (CHIRP), collaborating in a clinical research project with the ultimate goal of developing evidence-based, innovative management strategies for children with pneumonia.

In this trial we will observe how the body responds to an infection like pneumonia. The information we gather will help in the development of new ways of diagnosing and treating pneumonia.

Lacosamide as Therapy in Patients with Epilepsy

For complete study information, please visit clinicaltrials.gov.

Maintenance Chemotherapy or Observation Following Induction Chemo and Radiation for Ependymoma

Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients With Newly Diagnosed Ependymoma Ages 1 to 21 Years

Medical device study for patients with a rare kidney disease (Focal Segmental Glomerulosclerosis)

Treatment of Drug-Resistant Pediatric Focal Segmental Glomerulosclerosis Using the Liposorber ® LA-15 System

Motion Capture to Assess Function of Upper Extremities in Typically Developing Children

Motion Capture to Assess Function of Upper Extremity in Typically Developing Children

My Life Our Future: A Hemophilia Data and Sample Research Repository

My Life Our Future: A Hemophilia Genotyping Initiative Data and Sample Research Repository

Neuroblastoma Biology Studies

For complete study information, please visit clinicalstudies.gov.

Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children With Cancer

ALTE07C1 Neuropsychological, Social, Emotional and Behavioral Outcomes in Children with Cancer: A Group wide Non-Therapeutic Study CIRB

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Omaveloxolone (RTA 408) for patients with mitochondrial myopathy

A Phase 2 Study of the Safety, Efficacy and Pharmacodynamics of RTA 408 in the Treatment of Mitochondrial Myopathy

Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1

Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus (TN-07) Protocol TN-07

Pediatric Spine Registry

Pediatric Spine Registry

Peginterferon Alfa-2b in Treating Younger Patients With Craniopharyngioma

PBTC-039: Phase II Study of Peginterferon alfa-2b (PEGIntron) for Pediatric Patients with Un-resectable or Recurrent Craniopharyngioma - Cincinnati

Perampanel as Adjunctive Therapy in Children 1 mo - 2 years with Epilepsy

An Open-Label Study With an Extension Phase to Evaluate the Pharmacokinetics of Perampanel (E2007) Oral Suspension When Given as an Adjunctive Therapy in Subjects From 1 Month to Less Than 24 Months (<2 years) of Age With Epilepsy

Post-Radiation Chemotherapy in Patients With Newly Diagnosed Ependymoma

Please visit clinicaltrials.gov for complete study information.

Preventing Type 1 Diabetes in Relatives at Risk

Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus

Prospective Database Registry of Scheuermann's Kyphosis

Prospective Database Registry of Scheuermann's Kyphosis

Prospective Database Registry of Scoliosis in Children with Cerebral Palsy

Prospective Database Registry Study of Scoliosis in Children with Cerebral Palsy

Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens

AALL05B1: A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens

Radiation Therapy Before Surgery in patients Non-Rhabdomyosarcoma Soft Tissue Sarcomas

ARST1321: Pazopanib Neoadjuvant Trial in Non-rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754)

Recovery after ECMO in children with Acute Respiratory Distress Syndrome

ASCEND (ARDS in Children and ECMO initiation strategies impact on Neuro-Development)

Reiki Therapy for symptom management

Reiki Therapy for Symptom Management : A Feasibility Study in Young Children receiving Palliative Care

Risk-Based Classification of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)

For complete study information, please visit clinicaltrials.gov.

Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer

Treatment of Children With All Stages of Hepatoblastoma With Temsirolimus (NSC#683864) Added to High Risk Stratum Treatment

ROCK Prospective Cohort Study for Osteochondritis Dissecans of the Knee

ROCK Comprehensive Prospective Cohort for Osteochondritis Dissecans of the Knee

Safety and effectiveness of oxybutynin in children (6-16 years) with neurogenic bladder

A Multi-Center, Double-Blind, Placebo-Controlled, Dose-Titration Study Evaluating the Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of Oxybutynin Chloride Topical Gel for the Treatment of Detrusor Overactivity Associated with a Neurological Condition in Pediatric Subjects

Safety and efficacy of ASP0367 in patients with primary mitochondrial myopathy

A Randomized, Double-blind, Placebo-controlled Adaptive Phase 2/3 Study with Open-label Extension to Assess the Efficacy, Safety and Tolerability of ASP0367 in Participants with Primary Mitochondrial Myopathy

Safety and Efficacy of Fesoterodine in Children with Bladder Overactivity

A 24-week Randomized, Open-label, Study To Evaluate The Safety And Efficacy Of Fesoterodine In Subjects Aged 6 To 17 Years With Symptoms Of Detrusor Over activity Associated With A Neurological Condition (Neurogenic Detrusor Over activity)

Safety and efficacy of MACI in Patients with Chondral or Osteochondral Knee Defects (PEAK)

A prospective, open-label, randomized, concurrent active-controlled, longitudinal, multicenter, phase 3 clinical study of the safety and efficacy of MACI in patients aged 10 to 17 years with symptomatic chondral or osteochondral defects of the knee due to osteochondritis dissecans or acute trauma (PEAK Clinical Trial)

Safety and Efficacy of Nexium in Pediatric Patients with Erosive Esophagitis

A Phase III Study to Assess the Efficacy and Safety of NEXIUM for Maintenance of Healing of Erosive Esophagitis in Pediatric Patients 1 to 11 Years of Age

Safety and Efficacy of Plecanatide in Children 6 to < 18 with Irritable Bowel Syndrome with Constipation (IBS-C)

A randomized, double-blind, placebo-controlled, dose ranging, parallel-group study of the efficacy and safety of Plecanatide in Children 6 to < 18 Years of Age with Irritable Bowel Syndrome with Constipation (IBS-C) Protocol: SP304202-14

Safety and efficacy of pregabalin in children 1 mo-<4 years with partial onset seizures

A double blind, placebo-controlled parallel-group, multicenter study of the efficacy and safety of pregabalin as adjunctive therapy in children 1 month through <4 years of age with partial onset seizures

Safety and efficacy of pregabalin in children 4-16 years old with partial onset seizures

A double blind, placebo-controlled parallel-group, multicenter study of the efficacy and safety of pregabalin as adjunctive therapy in children 4-16 years of age with partial onset seizures

Safety and Efficacy of Pregabalin in Children Aged 1 mo to 16 years with Seizures

A 12-month Open-label Study To Evaluate The Safety And Tolerability Of Pregabalin As Adjunctive Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-clonic Seizures

Safety and efficacy of Ravulizumab for pediatric patients with thrombocytic microangiopathy following hematopoetic stem cell transplantation

ALXN1210-TMA-314: A Phase 3, Open-label, Single Arm, Multicenter Study of Ravulizumab in Addition to Best Supportive Care in Pediatric Participants (from 1 month to < 18 years of age) with Thrombotic Microangiopathy (TMA) after Hematopoietic Stem Cell Transplantation (HSCT)

Safety and Efficacy of REN001 in patients with Primary Mitochondrial Myopathy

A double-blind, placebo-controlled study to evaluate the efficacy and safety of 24 weeks treatment with RNE001 in patients with primary mitochondrial myopathy

Safety and efficacy of Rimegepant for the treatment of migraine in pediatric patients ≥6 to <18 years of age

Phase 3, multicenter, randomized, double-blind, group sequential, placebo-controlled study to assess efficacy and safety of rimegepant for the treatment of migraine (with or without aura) in children and adolescents ≥ 6 to <18 years of age

Safety and efficacy of Selumetinib in adolescents with NF1 related plexiform neurofibromas (PN)

A Phase I, Single-Arm, Sequential Study to Evaluate the Effect of Food on the Gastrointestinal Toxicity and Pharmacokinetics of Selumetinib after Multiple Doses in Adolescent Children with Neurofibromatosis Type 1 (NF1) Related Plexiform Neurofibromas (PN)

Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA

An Open-label, Sequential, Ascending, Repeated Dose-finding Study of Sarilumab, Administered With Subcutaneous (SC) Injection, in Children and Adolescents, Aged 2 to 17 Years, With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) Followed by an Extension Phase

Scoliosis Outcomes Database Registry

Scoliosis Outcomes Database Registry

Screening Patients With Sickle Cell Disease for Kidney Damage

Screening Patients With Sickle Cell Disease for Kidney Damage

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

A Phase 1 and Phase II and Re-Treatment Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma

SHARE Pediatric Palliative Care Study

Pediatric Palliative Care Research Network SHARE Study

Single vs. Multiple Privigen Dose Regimens in Pediatric CIDP

Randomized Study of Single vs. Multiple Privigen Dose Regimens in Pediatric CIDP

Somapacitan Once a Week with Daily Norditropin® in Children Who Need Help to Grow

A study comparing the effect and safety of once weekly dosing of somapacitan with daily Norditropin® as well as evaluating long-term safety of somapacitan in a basket study design in children with short stature either born small for gestational age or with Turner syndrome, Noonan syndrome, or idiopathic short stature

STOP 360: Standardizing Treatments for Pulmonary Exacerbations: A platform for evaluating treatment decisions to improve outcomes

Standardizing Treatments for Pulmonary Exacerbations: A platform for evaluating treatment decisions to improve outcomes

STOP2 – Standardized Treatment of Pulmonary Exacerbations

Standardized Treatment of Pulmonary Exacerbation II (STOP2) Protocol No: STOP2-IP-15

StrataGraft® in Deep Partial Thickness (DPT) Thermal Burns

A Phase 3 Multicenter, Single-Arm, Open-Label Study Evaluating the Safety, Tolerability and Efficacy of StrataGraft® Construct in Pediatric Subjects with Deep Partial Thickness (DPT) Thermal Burns

Study of Biomarkers found in Newborns with Down Syndrome and the Link to Leukemia

AAML08B: Biology Study of Transient Myeloproliferative Disorder (TMD) in Children With Down Syndrome (DS)

Study of Blood Samples From Newborns With Down Syndrome

AAML08B1: Biology Study of Transient Myeloproliferative Disorder (TMD) in Children With Down Syndrome (DS)

Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

Study of Cognitive effects of antiepileptic drugs in children with new-onset seizures

Cognitive effects of commonly prescribed antiepileptic drugs in children with new-onset seizures: a prospective longitudinal study

Study of Scoliosis Correction in patients with Marfan Syndrome

Study of Scoliosis Correction in Marfan Syndrome Patients

Sucraid® Oral Solution to treat Congenital Sucrase-Isomaltase Deficiency (CSID)

Evaluation of a 7-Day Therapeutic Trial Dose of Commercial Sucraid® (sacrosidase) Oral Solution for Alleviating Congenital Sucrase-Isomaltase Deficiency (CSID) Symptoms in Pediatric Subjects with Low, Moderate, and Normal Sucrase Levels

Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

This study being completed in collaboration with Cincinnati Children's Hospital. For complete information please visit clinicaltrials.gov

Teaching Parents Reiki Therapy

Teaching Parents Reiki for Their Adolescents Receiving Palliative Care

The CARRA Registry for Pediatric Rheumatic Diseases

Observational Study Of Pediatric Rheumatic Diseases: The CARRA Registry

The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

APEC14B1 - The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

The Severe Chronic Neutropenia International Registry (SCNIR)

Severe Chronic Neutropenia International Registry Protocol

Tissue Collection from patients with Cutaneous Non-Hodgkin Lymphoma

ANHL04B1: Rare And Cutaneous Non-Hodgkin Lymphoma Registry

Treating Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Risk-Stratified Therapy for Acute Myeloid Leukemia in Down Syndrome

Treating Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia

A Phase 1/2 Study of CPX-351 (NSC# 775341) Alone Followed by Fludarabine, Cytarabine, and G-CSF (FLAG) for Children With Relapsed Acute Myeloid Leukemia (AML)

Treating Younger Patients With T-Cell ALL or Stage II-IV T-Cell Lymphoblastic Lymphoma

A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T-Lymphoblastic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LLy)

Tretinoin and Arsenic Trioxide in Patients With Untreated Acute PML

A Phase III Study for Patients With Newly Diagnosed Acute Promyelocytic Leukemia (APL) Using Arsenic Trioxide and All-trans Retinoic Acid

Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia

AAML 1331, A Phase III Study for Patients with Newly Diagnosed Acute Promyelocytic Leukemia (APL) using Arsenic Trioxide and All-Trans Retinoic Acid: A COG Group wide Phase III Study

Umbrella Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

Umbrella Long-Term Follow-Up Protocol

Zolmitriptan Nasal Spray for Acute Migraine Treatment in 6 to 11 year olds

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Crossover Study To Evaluate The Efficacy And Safety Of Zolmitriptan Nasal Spray For The Treatment Of Acute Migraine In Subjects Ages 6 To 11 Years, With An Open-Label Extension