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Exercise in Patients with Mitochondrial Myopathy

How children and adults with mitochondrial myopathy respond to exercise


We’re trying to learn how people with mitochondrial myopathy respond to exercise. Mitochondria are the body’s "power plants." They turn food into energy. If the "power plants” don’t make enough energy, muscles may grow weak.

We’re studying differences between mitochondrial myopathy patients and healthy children when exercising. An exercise test tells us about breathing, blood circulation and muscle function during exercise.

Such studies may lead to exercise testing as a way to diagnose and monitor mitochondrial myopathy patients.

Who May Qualify?:

People with a certain or probable mitochondrial myopathy diagnosis between ages 6 through 60 years

Who Does Not Qualify:

Patients with:

  • Cardiomyopathy or conduction defects
  • Any absolute exercise testing restrictions as listed in American Thoracic Society guidelines (ATS 2003)
Study Status:
Study Sponsor:

Akron Children's Foundation

Full IRB Study Title:
Physiological manifestations of exercise intolerance in children (and adults) with mitochondrial myopathies
IRB Study ID:
If you are interested in this study or have questions about your child's eligibility, please contact:

Rebecca D. Considine Research Institute, 330-543-5012

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