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Genes that influence the body's response to infection

Genes that influence the way your body responds to infection


The purpose of this research study is to study whether it is possible to measure changes in thousands of genes that influence the way your body responds to an infection (germ), and to study whether these changes can predict the severity and course your illness, in addition to generating a database of gene expression patterns.

Who May Qualify?:

Children under 10 years of age, admitted to the Pediatric Intensive Care Unit with a diagnosis of septic shock.

Who Does Not Qualify:

Children greater than 10 years of age or those without a diagnosis of septic shock.

Interested in participating?
We are currently recruiting
Study Sponsor:

Cincinnati Children's Hospital

Full IRB Study Title:
Genomic Analysis of Pediatric Systemic Inflammatory Response Syndrome (SIRS) and The Pediatric Sepsis Biomarker Risk Model (PERSEVERE)
IRB Study ID:
If you are interested in this study or have questions about your child's eligibility, please contact:

Heather Anthony
Clinical Research Nurse

Lead Investigator
Michael Bigham, MD, MBA, FAAP, FCCM

Chief Quality Officer; Pediatric Intensivist
Pediatric Critical Care Medicine (PICU)

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