Skip to main content
Go to homepage

Print Page

Infantile Spasms

What Are Infantile Spasms?

Infantile spasms is a rare but serious type of epilepsy. It's associated with a unique, very abnormal brain wave pattern that can cause serious harm to a young, developing brain. This seizure type can happen during the first 2 years of life, most commonly between 5–7 months of age.

Babies with the condition also might have slowed development or loss of skills (like babbling, sitting, or crawling). The spasms can be very hard to control, and many children go on to have other kinds of seizures later in life.

The term West syndrome is used when a baby has infantile spasms, a unique EEG pattern (called hypsarrhythmia), and developmental delay.

What Do Infantile Spasms Look Like?

Spasms start suddenly and last a second or two. They often come one after another in a cluster that lasts several minutes. They happen most often just after a child wakes up. They're often mistaken for startles, colic, reflux, or hiccupping.

A baby having a spasm might have:

  • the head bent forward with arms flung out and the knees pulled into the body (described as "jackknife")
  • the head bent back with the arms and legs straightened
  • small movements in the neck or other parts of the body, such as the eyes widening and rolling up

What Causes Infantile Spasms?

Infantile spasms can be caused by problems with the way the brain developed in the womb, infections, brain injury, or abnormal blood vessels in the brain (such as an arteriovenous malformations). Infantile spasms also can happen in babies with some types of metabolic and genetic disorders. In rare cases, a baby's infantile spasms are caused by vitamin B6 deficiency.

More and more gene mutations are being linked to infantile spasms. Often, the cause isn't known.

How Are Infantile Spasms Diagnosed?

Infantile spasms are diagnosed by a pediatric neurologist (a doctor who treats brain, spine and nervous system problems). Testing may include:

  • blood tests and urine tests (to look for infections or illnesses)
  • EEG to see brain waves/electrical activity in the brain. The hypsarrhythmia pattern often confirms the diagnosis, but not every child with infantile spasms will have this.
  • VEEG, or video electroencephalography (EEG with video recording)
  • CAT scan, MRI, and PET/MRI scans to look inside the brain

How Are Infantile Spasms Treated?

Infantile spasms usually are treated with seizure medicines or steroids. If medicines don't control the spasms, a special diet, such as the ketogenic diet, might help. Sometimes, doctors may recommend surgery.

What Problems Can Happen?

Infantile spasms can lead to cognitive, neurologic, and/or sensory problems. Most children with infantile spasms will have problems with their development, and may need help with daily tasks throughout their lives.

How Can I Help My Child?

To help your child, follow the doctor's instructions to:

  • Give any medicines as prescribed.
  • Go for developmental assessments and therapies.
  • Go to all follow-up medical visits.

Your doctor and the care team can answer questions and offer support. They also might be able to recommend a local support group. Online organizations can help too, such as:

Reviewed by: Lily Tran, MD, Andrew I. Mower, MD
Date Reviewed: Feb 15, 2022

Lea este articulo en Español

What next?

Summit Mall Play Area
Answer Key:
Click to expand
There are 10 nurses in the picture.

And we have many more pediatric primary care providers in Northeast Ohio. You can meet some of them here.
Summit Mall Play Area
Answer Key:
Click to expand
The five differences are:
– Phone color
– Coat pocket
– Stethoscope earpiece color
– Stethoscope bell dot
– Clipboard paper color

Need help finding a doctor, choosing a location or getting a general question about Akron Children's answered? Call us or fill out the form and we'll help in any way we can.
Summit Mall Play Area
Answer Key:
Click to expand
The two matching doctors are 9 and 14.

With virtual visits, you can see our pediatric experts from the comfort of home or wherever you are.
Summit Mall Play Area
Answer Key:
Click to expand
The correct path:
The Correct Path
We offer many ways to get pediatric care all over Northeast Ohio. Use this page to find the right kind of care and the most convenient location for you.