We are experiencing exceptionally high volumes in our emergency rooms.
Every patient is important to us, and we are doing all we can to provide care quickly and efficiently.
Skip to main content
Go to homepage

Print Page

A to Z: Hypogammaglobulinemia

Hypogammaglobulinemia (HI-po-GAM-uh-GLOB-you-luh-NEE-mee-uh) is an abnormally low level of immunoglobulins (antibodies also called proteins that help fight infections) in the blood.

More to Know

The body's immune system uses white blood cells, or leukocytes, to seek out and destroy disease-causing organisms or substances. Lymphocytes are a type of white blood cell, and the two types of lymphocytes are B lymphocytes and T lymphocytes.

B lymphocytes produce antibodies (immunoglobulins) that target foreign substances for destruction. When someone has hypogammaglobulinemia, his or her body is lacking in B lymphocytes. This leads to low levels of immunoglobulins, making the person more likely to be infected by a bacteria or virus.

Doctors don't always know what causes hypogammaglobulinemia, but it can be present at birth (congenital) or develop later in life (acquired). People with hypogammaglobulinemia typically have a lot of respiratory problems, sinus and ear infections, and gastrointestinal disorders. They also face a greater risk of more serious infections.

Keep in Mind

Most children born with transient hypogammaglobulinemia of infancy will grow out of it between the ages of 2 and 5. Other types of hypogammaglobulinemia are lifelong conditions. The risk of infection can be reduced by different treatments, depending on the type and cause of hypogammaglobulinemia. One of the more common treatments is an intravenous (IV) form of replacement immunoglobulins.

All A to Z dictionary entries are regularly reviewed by KidsHealth medical experts.

What next?

Summit Mall Play Area
Answer Key:
Click to expand
There are 10 nurses in the picture.

And we have many more pediatric primary care providers in Northeast Ohio. You can meet some of them here.
Summit Mall Play Area
Answer Key:
Click to expand
The five differences are:
– Phone color
– Coat pocket
– Stethoscope earpiece color
– Stethoscope bell dot
– Clipboard paper color

Need help finding a doctor, choosing a location or getting a general question about Akron Children's answered? Call us or fill out the form and we'll help in any way we can.
Summit Mall Play Area
Answer Key:
Click to expand
The two matching doctors are 9 and 14.

With virtual visits, you can see our pediatric experts from the comfort of home or wherever you are.
Summit Mall Play Area
Answer Key:
Click to expand
The correct path:
The Correct Path
We offer many ways to get pediatric care all over Northeast Ohio. Use this page to find the right kind of care and the most convenient location for you.