Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). HCV can lead to liver failure, liver cancer, or chronic liver disease (cirrhosis). HCV infections are a leading reason for liver transplants in the United States.
Some people with HCV have just a short-term illness because their bodies can get rid of the virus. But most infected people (70%–85%) develop a chronic (long-lasting) HCV infection.
HCV spreads by direct contact with an infected person's blood and other body fluids. This can happen through:
Thanks to blood screening and other health care safety rules adopted in the early 1990s, the spread of HCV from hemodialysis, blood transfusions, or organ transplants is now rare.
It's also rare, but possible, for someone to get HCV by sharing household items that might contain an infected person's blood, such as razors, toothbrushes, or scissors.
HCV is more common in adults than in kids. Rates of HCV infection in the United States almost tripled from 2010 to 2015, according to the Centers for Disease Control and Prevention (CDC).
Most of these new infections are in young adults (20 to 29 years old) who inject drugs. Many of them went from abusing prescription drugs to injecting heroin, which often is cheaper and easier to get. Health experts worry that more newborns will be at risk for HCV because so many young women are part of this group.
Doctors refer to hepatitis C infections as either acute or chronic:
Most people with HCV have no symptoms. But even without symptoms, they can develop health problems decades later and can still pass the disease to others.
If symptoms do happen, it's usually when the disease is very advanced. Symptoms can be similar to those of hepatitis A and hepatitis B and include:
Hepatitis C is the most serious type of hepatitis. It's now one of the most common reasons for liver transplants in adults. Every year, almost 20,000 people in the United States die from HCV.
Fortunately, medicines can now treat people with hepatitis C and cure them in most cases.
Doctors do a blood test to look for antibodies to hepatitis C. If antibodies are present, it only means that the person has had an HCV infection at some point. To see if the disease is still active, doctors do another test to measure the level of HCV in the blood.
The CDC recommends the diagnostic blood test for:
Significant progress has been made in treating and even curing hepatitis C. Older hepatitis C treatments usually required weekly injections, had serious side effects, and often were not effective.
New and better oral medicines now can cure HCV for many people within 3 months. The new medicines were very expensive at first, but their prices have come down, a trend that health experts hope will continue as the incidence of HCV rises and increased screening brings more cases to light.
These medicines successfully cure about 90% of HCV patients. A new oral medicine under development looks promising for the 10% who don't respond to the standard treatment. This new antiviral combination pill is currently under review by the U.S. Food and Drug Administration (FDA).
As with hepatitis B, anyone who has ever tested positive for hepatitis C cannot be a blood donor.
People who had HCV as a result of drug use should get counseling or further treatment to help them overcome their addiction. Otherwise, they could become reinfected with HCV.
Unfortunately, there's no vaccine to protect against hepatitis C. Prevention means avoiding risky behaviors that can spread HCV, especially injecting drugs.
Reviewed by: Jolanda M. Denham, MD
Date Reviewed: Aug 1, 2017
