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Akron Children's > For Families & Patients > Research > Pediatric Clinical Studies > Open Clinical Studies

Study of Cognitive effects of antiepileptic drugs in children with new-onset seizures

Full IRB Study Title:
Cognitive effects of commonly prescribed antiepileptic drugs in children with new-onset seizures: a prospective longitudinal study

IRB Study ID: 1030094-1

Epilepsy is the most common neurologic disorder in children affecting 4-6 per 1000 children Antiepileptic drugs (AEDs) are the primary, and frequently exclusive, treatment option for epilepsy. While necessary and effective for seizure control, AEDs can also cause neurotoxicity, adversely affecting functioning of the central nervous system. This study aims to evaluate patients before starting AED’s  to evaluate any possible side effects or difference in the child’s ability to perform certain tasks (cognitive functioning)  The purpose of the proposed study is to examine the cognitive and behavioral effects of commonly prescribed AEDs on children with new onset seizures. This will be accomplished by recruiting children who are seen in the new onset seizure clinic in the Neurology service of the Neuro Developmental Science Center (NDSC) at Akron Children’s.

Study Sponsor:

Akron Children’s Foundation

Who May Qualify:

Children that have been diagnosed with new-onset seizures.

Who Does NOT Qualify:

Children that have already begun prescribed treatments for their epilepsy. 

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