Respiratory Panel Film Array
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| 1. Respiratory Panel Film Array | |
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(Published August 2025)
Some patients with respiratory symptoms will benefit from testing for specific pathogens, though it will not change management in many patients. Patients admitted to the hospital with respiratory distress that is suspected to be infectious should have COVID-19 testing done, as this will impact isolation and treatment options. Rapid testing can be done with both the 4-plex PCR assay (SARS-CoV2/Flu A-B/RSV) and RFA (Respiratory Panel Film Array). The 4-plex PCR assay is the preferred option in most cases. Most patients well enough to be discharged from the ED should only have testing done if it will change management.
Scenarios to consider ordering an RFA rather than 4-plex assay up front where the result is likely going to change management:
• Possible need for PICU care for respiratory reasons
• Immunocompromise
• Prolonged fever
• Complex or chronic conditions
• Diagnostic dilemmas
• Patients under 60 days with fever
• When Mycoplasma is on the differential
Scenarios when initial RFA is not typically indicated:
• Known asthma
• URI and bronchiolitis that is being managed outpatient
• All scenarios where it is unlikely to change management

