Tube Type:
Red top (no anticoagulant) tube
Cause for Rejection:
Specimen rejected: Grossly icteric.
Methodology:
Heat Activation, Fluorometric, Automated
Special Instructions:
Serum assay results are not valid on pregnant females and will not be run. If carrier screening for Tay-Sachs or Sandhoff disease is desired in a pregnant female and testing was not performed prior to pregnancy, referto NAGR / Hexosaminidase A and Total, Leukocytes/Molecular Reflex or NAGW/ Hexosaminidase A and Total Hexosaminidase, Leukocytes for testing on the patient or partner. The recommended test for Tay-Sachs carrier screening (regardless of gender or pregnancy status) is NAGR / Hexosaminidase A and Total, Leukocytes/Molecular Reflex.
Please have patient fill out the Mayo Medical Laboratories' Tay-Sachs Disease Prevention Program Questionnaire. Pregnant females can't be tested. It is suggested that the baby's father be tested for carrier status. If father is a positive carrier, the pregnant female should have Hexosaminidase A & Total Leukocytes.
For Outpatients, test should only be drawn in outpatient locations within a Hospital (Akron or Beeghly).