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Akron Children's > For Healthcare Professionals > Lab Tests : Akron | Mahoning Valley

FISH, Bone Marrow

PATIENT INFO
Patient Name:
Medical Record #:
BD:       /      /         Sex:   F   M

PHYSICIAN INFO
Physician Name :
Address:
Ph: (      )      -          Fax: (      )      -       
Additional Report to:
Ph: (      )      -          Fax: (      )      -       

TESTS REQUESTED
Test Name: ICD9 Code: (required)
1. FISH, Bone Marrow  
2.  
3.  
4.  
5.  
6.  

SPECIMEN INFO
Collection Date & Time:
Collected By:
Hospital:
Test ID :
LAB4721
Specimen Type:
3 mL bone marrow collected in sodium heparin (green top) tube for FISH and Chromosome Analysis studies. Minimum volume is 1 mL for FISH analysis only.
Cause for Rejection:
Nonsterile, gross contamination, or frozen specimen.
Storage:
Transport at room temperature. Upon arrival in laboratory, store refrigerated.
Availability:
Mon-Fri (0700-1600) Sun (0900-1300)
Methodology:
Fluorescent in situ hybridization. Images are captured digitally using image analysis software.
Special Instructions:
Include all pertinent medical findings with suspected diagnosis and/or indication(s) for testing.
Lab/Phone:
330-543-8483
TAT:
10 Days
Additional Info:

 

Available FISH Panels:

CEP4 and CEP10 Panel
(D4Z1, D10Z1)

Myelodysplastic Syndrome (MDS) Panel
(EGR-1, D7S486, IgH/MYC/CEP8, D20S108)

 B-Cell Acute Lymphoblastic Leukemia (B-ALL) Panel
(BCR/ABL ES, CEP 4/10, KMT2A(MLL), ETV6/RUNX1)

High Risk B-Cell Acute Lymphoblastic Leukemia (HRB-ALL) Panel
(BCR/ABL ES, CEP 4/10, KMT2A(MLL), ETV6/RUNX1, ABL1, ABL2, PDGFRB)

T-Cell Acute Lymphoblastic Leukemia (T-ALL) Panel
(BCR/ABL ES, KMT2A(MLL))

Acute Myeloid Leukemia (AML) Panel
(EGR-1, D7S486, KMT2A(MLL), RUNX1T1/RUNX1, CBFB)

AAML1031 Panel
(EGR-1, D7S486, KMT2A(MLL), RUNX1T1/RUNX1, BCR/ABL ES, PML/RARA)

MYC Lymphoma Panel
(IgH/MYC/CEP8, C-MYC)

Available FISH Probes:

 ABL1 (9q34) 
 ABL2 (1q25.2)
 ALK (2p23)
 BCR/ABL t(9;22) 
 CBFB/MYH11 (inv16) 
 CEP4 (D4Z1) 
 CEP10 (D10Z1) 
 D20S108 (del20q) 
 D7S486 (-7/del 7q) 
 EGR-1 (-5/del 5q) 
 ETV6/RUNX1 (TEL/AML1) t(12;21) 
 EWSR1 (22q12) 
 IgH/MYC/CEP8 t(8;14) 
 KMT2A (MLL) (11q23) 
 MYC (8q24) 
 N-MYC (2p24.1) 
 PDGFRB (5q32) 
 PML/RARA t(15;17) 
 RUNX1T1/RUNX1 (ETO/AML1) t(8;21)

CPT Code:

88271 (DNA probe, each)
88275 (Interphase in situ hybridization, 100 to 300 cells, each)
88291 (Interpretation and Report)

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