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Akron Children's > For Healthcare Professionals > Lab Tests : Akron | Mahoning Valley

FISH, Blood

PATIENT INFO
Patient Name:
Medical Record #:
BD:       /      /         Sex:   F   M

PHYSICIAN INFO
Physician Name :
Address:
Ph: (      )      -          Fax: (      )      -       
Additional Report to:
Ph: (      )      -          Fax: (      )      -       

TESTS REQUESTED
Test Name: ICD9 Code: (required)
1. FISH, Blood  
2.  
3.  
4.  
5.  
6.  

SPECIMEN INFO
Collection Date & Time:
Collected By:
Hospital:
Test ID :
LAB4738
Specimen Type:
3 mL whole blood collected in sodium heparin (green top) tube for FISH and Chromosome Analysis studies. Minimum volume is 1 mL for FISH analysis only.
Cause for Rejection:
Nonsterile, gross contamination, or frozen specimen.
Storage:
Transport blood at room temperature. Upon arrival in laboratory, store refrigerated.
Availability:
Mon-Fri (0700-1600) Sun (0900-1300)
Methodology:
Fluorescent in situ hybridization. Images are captured digitally using image analysis software.
Special Instructions:
Include all pertinent medical findings with suspected diagnosis and/or indication(s) for testing.
Lab/Phone:
330-543-8483
TAT:
Constitutional FISH: 28 Days
Neoplastic FISH: 10 Days
Additional Info:

 

Available FISH Panels:

Aneuploidy Analysis
(CEPX/Y/18, CEP13/21)

Sex Chromosome Analysis, Ambiguous Genitalia
(CEPX/Y/18, SRY (Yp11.2) / DYZ1 (Yq12))

Analysis for Sex Mismatched Bone Marrow Transplant
 (DXZ1 & DYZ1)

CEP4 and CEP10  Panel
(D4Z1, D10Z1)

Myelodysplastic Syndrome (MDS)  Panel
 (EGR-1, D7S486, IgH/MYC/CEP8, D20S108)

B-Cell Acute Lymphoblastic Leukemia (B-ALL) Panel
(BCR/ABL ES, CEP 4/10, KMT2A(MLL), ETV6/RUNX1)

High Risk B-Cell Acute Lymphoblastic Leukemia (HRB-ALL) Panel
(BCR/ABL ES, CEP 4/10, KMT2A(MLL), ETV6/RUNX1, ABL1, ABL2, PDGFRB)

T-Cell Acute Lymphoblastic Leukemia (T-ALL) Panel
(BCR/ABL ES, KMT2A(MLL))

Acute Myeloid Leukemia (AML) Panel
 (EGR-1, D7S486, KMT2A(MLL), RUNX1T1/RUNX1, CBFB)

AAML1031 Panel
(EGR-1, D7S486, KMT2A(MLL), RUNX1T1/RUNX1, BCR/ABL ES, PML/RARA)

Available FISH Probes:

ABL1 (9q34) 
ABL2 ( 1q25.2)
BCR/ABL t(9;22)
CBFB/MYH11 (inv16)
CEP12
CEP13/18
CEPX/Y/18
D13S319 (13q14.3)
D7S486 (-7/del 7q)
D20S108 (del20q)
DYZ1 (Yq12)
EGR-1 (-5/del 5q)
ETV6/RUNX1 (TEL/AML1) t(12;21)
HIRA (22q11.2)/ARSA (22q13.3)
IgH/MYC/CEP8 t(8;14)
KMT2A (MLL) (11q23)
PDGFRB (5q32)
PML/RARA t(15;17)
RUNX1T1/RUNX1 (ETO/AML1) t(8;21)
SRY (Yp11.2)/DYZ1 (Yq12)
XIST (Xq13.2)

CPT Code:
88271 (DNA probe, each)
88275 (Interphase in situ hybridization, 100 to 300 cells, each)
88291 (Interpretation and Report)

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