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Aspergillus galactomannan Antigen

Centralized Core Laboratory - Mayo Clinic Laboratories : Send Out

Test ID :
ASGAL
Test Workstation :
MAYO
Specimen Type:
Serum
Tube Type:
Gold top SST (serum separator tube, no anticoagulant)
Collection Volume:
4.0 mL
Minimum Volume:
2.5 mL
Cause for Rejection:
Tube opened, or poured off
Storage:
Refrigerated
Availability:
Sent to reference laboratory
Methodology:
Enzyme Immunoassay (EIA)
Special Instructions:
Send specimen in original container. Do not Aliquot. Two or more consecutive positive results should be obtained from separately drawn specimens before the patient is considered to have a positive Aspergillus antigen test. False positive results can be caused by: Piperacillintazobactam and a few other antibiotics; plasmalyte and other fluids containing sodium gluconate; Infection with Penicillium, Alternaria and Paecilomyces; Histoplasmosis, and possibly other endemic mycoses. The Platelia(r) Aspergillus EIA kit was evaluated for sensitivity (52.9% and 79.3%) and specificity (87.0% and 88.8%) in the multicenter US study that led to its FDA clearance of serum for pediatric and adult patients, respectively. The performance of this assay has not been evaluated with neonate samples. Antifungal therapy may reduce the assay's sensitivity.
Lab/Phone:
330-543-8418
TAT:
1-4 days
Additional Info:
Reference range:
  • Aspergillus galactomannan Ag: Range: <0.5 Index
  • Days Performed: Mon-Fri
  • CPT Code:
    87305

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