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Amitri/Nortriptyline

Centralized Core Laboratory : Chemistry

Test ID/Workstation :
AMINT MAYO
Specimen Type:
Blood
Tube Type:
Red top (no anticoagulant) tube
Collection Volume:
2.5 mL (1.0 mL minimum)
Storage:
Refrigerated
Availability:
Sent to reference lab
Methodology:
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Special Instructions:
Collect immediately prior to next dose. Centrifuge and take off cells within 2 hours of collection. If collected at an offsite location, send by a STAT Courier to Hospital lab (Akron or Mahoning Valley).
Lab/Phone:
330-543-8418
TAT:
3-5 days
Additional Info:
  • Reference range:
  • Amitriptyline 80-200 ng/mL. Risk of toxicity is increased with combined levels are above 500 ng/mL.
  • Nortriptyline 70-170 ng/mL. Risk of toxicity is increased with nortriptyline levels above 500 ng/mL.
  • Therapeutic ranges are based on specimens collected at trough (ie, immediately before the next dose).
  • CPT Code:
    80335
    Panel Includes:
    Amitriptyline; Nortriptyline; Total Amitrip/Nortriptyline
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