Objectives (Educational Content) :
1. Recognize clinical signs and symptoms of hyperinflammation.
2. Illustrate the mechanisms underlying hyperinflammation and identify associated inborn errors of immunity.
3. Describe treatment options for hyperinflammation and HLH.
Target Audience:
General pediatricians, family physicians, nurse practitioners, physician assistants, social workers, psychologists, and nurses.
Identified Gap:
Pediatric healthcare providers need enhanced clinical knowledge and diagnostic skills to have appropriate suspicion and evaluate for Hemophagocytic Lymphohistiocytosis (HLH). Education is needed to support differentiation of HLH from similar appearing systemic illnesses, guide appropriate evaluation, and inform decisions regarding timely subspecialty referral.
Estimated Time to Complete the Educational Activity:
1 hour(s)
Expiration Date for CE/CME Credit:
12-11-2026
Method of Participation in the Learning Process:
The learner will view the presentation, successfully complete a post-test and complete an activity evaluation.
Evaluation Methods:
All learners must successfully complete a post-test, as well as an activity evaluation, to claim CE/CME credit.
Disclosure:
The speaker(s) has returned the disclosure form, indicating that there are no financial relationships with ineligible companies: Melissa J. Rose, DO The following CME Committee/Planning Committee member(s) has the following financial relationships with ineligible companies to disclose: Merck - Maria Cristina Victorio, MD Moderna, Pfizer and Merck - Shefali Mahesh, MD All financial relationships have been mitigated.
Accreditation Statement:
Children’s Hospital Medical Center of Akron is accredited by the Ohio State Medical Association to provide continuing medical education for physicians.
CHMCA designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit TM. Physicians should only claim the credit commensurate with the extent of their participation in the activity.
Bibliography:
1. Abdelhay et al, eClinical Medicine 2023
2. Pediatr Blood Cancer. 2019 Nov; 66(11): e27929.
3. ARTHRITIS & RHEUMATOLOGY, Vol. 66, No. 9, September 2014, pp 2613–2620
