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Grand Rounds: Neurobiology of Addiction


By William Goldman, DO , Medical Director, Addiction Service Program, Akron Children's Hospital, Akron, OH

Addiction Services Program

More about William Goldman, DO

Objectives (Educational Content) :

1. Demonstrate a comprehensive understanding of general neurobiology and neurobiology of adolescent brain development. 2. Explain how substance use can have long-term ramifications. 3. Develop an effective approach on addressing substance use as medical providers with our families.

Target Audience:

General pediatricians, family physicians, nurse practitioners, physician assistants, social workers, psychologists and nurses

Identified Gap:

Improved awareness of the effects on the brain of adolescent substance abusers will aid families in dealing with these patients.

Estimated Time to Complete the Educational Activity:

1 hour

Expiration Date for CME Credit:


Method of Physician Participation in the Learning Process:

The learner will view the presentation, successfully complete a post-test and complete an activity evaluation.

Evaluation Methods:

All learners must successfully complete a post-test, as well as an activity evaluation, to claim CME credit.


Dr. Goldman has indicated that he has no relevant financial interest in any pharmaceutical or medical device company and that this activity was developed independent of commercial interest.

Accreditation Statement:

Children’s Hospital Medical Center of Akron is accredited by the Ohio State Medical Association to provide continuing medical education for physicians.

CHMCA designates this enduring material activity for a maximum of 125 AMA PRA Category 1 Credit TM.  Physicians should only claim the credit commensurate with the extent of their participation in the activity.


PNAS 101:8174=8179, ©2004 National Academy of Sciences, U.S.A. 

Casey BJ, et al., Development Reviews. 2008: 62-77

Hingson RW, Heeren T, Winter MR.  Age at drinking onset and alcohol dependence: Age at onset, duration, and severity. Arch Pediatr Adolesc Med. 2006; 160(7):739-746.

Winters KC, Lee C-YS.  Likelihood of developing an alcohol and cannabis use disorder during youth: association with recent use and age. Drug Alcohol Depend. 2008;92(1-3):239-247.