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Grand Rounds: Therapeutic Management of Patients with COVID-19


By Shankar Upadhyayula, MD, Director, Pediatric Infectious Disease; Kelly Williamson, PharmD , Akron Children's Hospital, Akron, OH

Objectives (Educational Content) :

1. Explain outpatient management of SARS-CoV-2 infection including prevention and treatment. 2. Evaluate therapeutic options for hospitalized patients with COVID-19. 3. Summarize treatments not recommended for COVID-19.

Target Audience:

General pediatricians, family physicians, nurse practitioners, physician assistants, social workers, psychologists, and nurses.

Identified Gap:

Update on prevention and treatment of patients with COVID-19.

Estimated Time to Complete the Educational Activity:

1 hour(s)

Expiration Date for CE/CME Credit:


Method of Participation in the Learning Process:

The learner will view the presentation, successfully complete a post-test and complete an activity evaluation.

Evaluation Methods:

All learners must successfully complete a post-test, as well as an activity evaluation, to claim CE/CME credit.


Drs. Upadhyayula and Williamson have indicated that there are no relevant financial or other relationships with any commercial interests and that this activity was developed independent of commercial interest.

Accreditation Statement:

Regeneron EUA HCP Fact Sheet 09172021 (

Caly, et al. Antiviral Res2020; 178:104787

Muthu V et al.  Mycopathologica. 2021 Aug 19.

Lancet Microbe 2021; 2: e354-65 Published Online June 2, 2021.

Jiang S, et al. Trends Immunol 2020; 41: 355-9.

Schmith V, et al. Clin Pharmacol Ther 2020; 108(4): 762-765.

Recovery Trial: Dexamethasone in Hospitalized Patients with COVID-19. N Engl J Med 2021; 384:693-704.


2019 Infant Mortality Annual Report. (2020, December 21). Ohio Department of Health. Infant+Mortality+Report+2019.pdf (

Ohio Department of Health. (2021, August 6). Infant Safe Sleep [Web page]. Retrieved from Infant Safe Sleep | Ohio Department of Health

American Academy of Pediatrics Policy Statement. (2016). SIDS and Other Sleep-Related Infant Deaths: updated 2016. DOI: 10.1542/peds.2016-2938

Akron Children's Hospital, (2020-2021). Safe Sleep Academy [Web page]. Retrieved from

Trohman L, Williams BW, Wuensch H, et al. (2019, October 24). Akron Children's Hospital 2019 Community Health Needs Assessment Executive Summary [Web page]. Retrieved from

Larberg, Ndidi. (2019, October). Annual Report, Maternal Child Health. Summit County Public Health.

Synergy International Limited, Inc. (2021, January). Summit County Safe Sleep Research Summary Report

Michigan Department of Health & Human Services, (2021). Helping Families Practice Infant Safe Sleep [Web page]. Retrieved from

Ohio Department of Health, (2021, August 6). Infant Safe Sleep [Web page]. Retrieved from

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