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Grand Rounds: Influenza Disease and Vaccines in Specialized Populations

01-20-2023

By Natasha Halasa, MD , Craig Weaver Professor of Pediatrics, Pediatric Infectious Diseases, Vanderbilt University


Objectives (Educational Content) :

1. Explain influenza disease and epidemiology. 2. Describe prior influenza vaccine studies in specialized populations. 3. Identify alternative vaccine strategies in influenza trials in transplant populations.

Target Audience:

General pediatricians, family physicians, nurse practitioners, physician assistants, social workers, psychologists, and nurses.

Identified Gap:

New information in treatment of influenza in specialized populations.

Estimated Time to Complete the Educational Activity:

1 hour(s)

Expiration Date for CE/CME Credit:

01-19-2024

Method of Participation in the Learning Process:

The learner will view the presentation, successfully complete a post-test and complete an activity evaluation.

Evaluation Methods:

All learners must successfully complete a post-test, as well as an activity evaluation, to claim CE/CME credit.

Disclosure:

The speaker, Natasha Halasa, MD, has returned the disclosure form indicating the following relationships: Sanofi: Grant recipients/donated vaccines and performed HAL testing. Quidel: Performed viral testing and grant support. Genentech: Educational grant funding. All the above relationships have ended. All relationships have been mitigated.

Accreditation Statement:

Children’s Hospital Medical Center of Akron is accredited by the Ohio State Medical Association to provide continuing medical education for physicians.

CHMCA designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit TM.  Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Bibliography:

N Engl J Med 2000 Jan 27;342(4):225-31. doi: 10.1056/NEJM200001273420401.

The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children

K M Neuzil 1, B G Mellen, P F Wright, E F Mitchel Jr, M R Griffin

Practice Guideline MMWR Recomm Rep 2022 Aug 26;71(1):1-28. doi: 10.15585/mmwr.rr7101a1.

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022-23 Influenza Season

Lisa A Grohskopf, Lenee H Blanton, Jill M Ferdinands, Jessie R Chung, Karen R Broder, H Keipp Talbot, Rebecca L Morgan, Alicia M Fry

N Engl J Med 2023 Jan 11. doi: 10.1056/NEJMc2210825. Online ahead of print.

Influenza Vaccine in Pediatric Recipients of Hematopoietic-Cell Transplants

Jennifer E Schuster 1, Lubna Hamdan 2, Daniel E Dulek 2, Carrie L Kitko 2, Einas Batarseh 2, Zaid Haddadin 2, Laura S Stewart 2, Anna Stahl 2, Molly Potter 2, Herdi Rahman 2, Spyros A Kalams 2, Susan Coffin 3, Monica I Ardura 4, Rachel L Wattier 5, Gabriela Maron 6, Claire E Bocchini 7, Elizabeth A Moulton 7, Michael Grimley 8, Grant Paulsen 8, Christopher J Harrison 1, Jason Freedman 3, Paul A Carpenter 9, Janet A Englund 9, Flor M Munoz 7, Lara Danziger-Isakov 8, Andrew J Spieker 10, Natasha Halasa 10; Pediatric HCT Flu Study Group

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