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Grand Rounds: How Viruses Emerge & Spread Among Humans; Migraines: A Practical Approach to the Pediatric Patient; Is Movement Disorders Phenomenology Still Important in the Era of Exome and Genome Sequencing?


By James F. Bale, Jr., MD, Professor of Pediatrics and Neurology, Univ. of Utah School of Medicine. Kenneth J. Mack, MD, PhD, Consultant, Dept. of Neurology, Mayo Clinic, Rochester, Minnesota , Jonathan W. Mink, MD, PhD, Professor, Dept of Neurology; Frederick A. Horner, MD, Distinguished Professor in Pediatric Neurology; Professor, Depts. of Pediatrics and Neuroscience, Univ. of Rochester Medical Center

Objectives (Educational Content) :

1. Identify mechanisms of virus emergence and transmission. 2. Describe current best approaches to the diagnosis and treatment of migraines. 3. Recognize the important role of the physical exam in the setting of the miraculous abilities and limitations of genomic sequencing.

Target Audience:

General pediatricians, family physicians, nurse practitioners, physician assistants, social workers, psychologists, and nurses.

Identified Gap:

Hower Award recognizing advances in virus management, migraines and genetics.

Estimated Time to Complete the Educational Activity:

1 hour(s)

Expiration Date for CE/CME Credit:


Method of Participation in the Learning Process:

The learner will view the presentation, successfully complete a post-test and complete an activity evaluation.

Evaluation Methods:

All learners must successfully complete a post-test, as well as an activity evaluation, to claim CE/CME credit.


James Bale, Jr., MD returned the disclosure form, indicating no relevant financial or other relationships with any commercial interest. Kenneth J. Mack, MD, PhD, has returned the disclosure form indicating relationships with the following companies: Eli Lilly, Biohaven, Upsher Smith, and AbbieVie, serving on the Data Monitoring Committees for all. Jonathan Mink, MD, PhD, indicated relationships with Neurogene, Inc., Amicus, Inc., PTC Therapeutics, PassageBio, Biogen and TEVA. Commercial/financial relationships for the above individuals have been mitigated.

Accreditation Statement:

Children’s Hospital Medical Center of Akron is accredited by the Ohio State Medical Association to provide continuing medical education for physicians.

CHMCA designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit TM.  Physicians should only claim the credit commensurate with the extent of their participation in the activity.


Duffy MR, et al. Zika Virus: Emergence and Human Disease: Consequence of Global Travel and Climate Change. N Engl J Med 2009;360:2536-43.

Aubry M, et al. Emerg Infect Dis 2017;23:669-72. 

de Fatima Vasco Aragao M, et al. Zika-Associated CNS Abnormalities in Congenital Infection. BMJ 2016.

Wang-Shick Ryu. New Emerging Viruses. Molecular Virology of Human Pathogenic Viruses, 2017.

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