Sex Chromosome Analysis by DNA FISH, Newborn Smear
Blood, Bone Marrow
Green top (sodium heparin) tube
Cause for rejection:
Clotted, non-sterile, or frozen specimen
Mon-Fri (0900-1600) Sat (0900-1300)
Smears are prepared and pretreated, hybridized overnight with appropriate DNA probe(s), washed, and counterstained. 100-300 cells are analyzed using a fluorescence microscope and images are captured digitally using image analysis software.
Typically in situ hybridization results can be confirmed by standard cytogenetic studies. Include pertinent medical findings on the requisition with suspected diagnosis and/or indication(s) for testing.
OC Power Word:
24 hours-5 days
Interpretation is provided with report
88271 (each probe), 88275, 88291
FISH; Fluorescent in situ hybridization