Grand Rounds: Hypermethylation of Candidate Tumor Suppressor Genes in Osteosarcoma

May 9, 2014

By Daniel Pettee, DO , Hematology/Oncology Fellow, Akron Children's Hospital , Cancer and Blood Disorders

Objectives (Educational Content) :
1. Recognize the role of DNA hypermethylation in cancer

2. Describe the role of data analysis in formulating experiments

3. Illustrate basic models for evaluating tumor cells in vitro

Target Audience:
Physicians, pediatricians and pediatric residents.

Identified Gap:
It is a requirement of the hematology/oncology fellowship curriculum that their fellows present their fellowship research prior to the end of their fellowship training.

Estimated Time to Complete the Educational Activity
1 hour

Method of Physician Participation in the Learning Process:
The learner will view the presentation, successfully complete a post-test and complete an activity evaluation.

Evaluation Methods:
All learners must successfully complete a post-test, as well as an activity evaluation, to claim CME credit.

Disclosure:
Dr. Daniel Pettee has indicated that he has not had financial or other relationships with any commercial interest during the past 12 months.

Accreditation Statement:
Children’s Hospital Medical Center of Akron is accredited by the Ohio State Medical Association to provide continuing medical education for physicians.

CHMCA designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit ™. Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Media Requirements:

  • Windows XP or above and Internet Explorer 6 (partial support) or above, or
  • Firefox 3.6 or 4.0 or the latest version of Chrome
  • Mac OS 10.5 or above and Firefox 3.6 or 4.0 or the latest version of Chrome or
  • Safari 4 or above
  • Linux with Firefox 3.6 or 4.0

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