Bruce H. Cohen, MD, FAAN

Bruce H. Cohen, MD, FAAN

Bruce H. Cohen, MD, FAAN

Director, NeuroDevelopmental Science Center




Neurology - Akron

Other Locations:
Neurology - Brecksville
Neurology - Hudson
NeuroDevelopmental Science Center

Medical School

Albert Einstein College of Medicine of Yeshiva University, Bronx, NY


Pediatrics, Children's Hospital of Philadelphia, PA

Pediatric Neurology, Neurological Institute of New York and Babies Hospital/Columbia Presbyterian Medical Center, New York, NY


Pediatric Neuro-Oncology, Children's Hospital of Philadelphia, PA

Board Certifications

American Board of Pediatrics
Child Neurology, American Board of Psychiatry and Neurology
National Board of Medical Examiners


Fellow, American Academy of Neurology
Child Neurology Society
President, Professors of Child Neurology
Mitochondrial Research Society
Mitochondrial Medicine Society
American Neurological Association


Hoch DB, Homonoff MC, Moawad MC, Cohen BC, Esper GJ, Becker A, Busis NA. The neurologist as a medical home neighbor. Neurol Clin Pract 2013;3;134.

Cohen BH. Neuromuscular and Systemic Presentations in Adults: diagnoses beyond MERRF and MELAS. Neurotherapeutics. 2013; 10: 227-242.

Saneto RP, Cohen BH, Copeland WC, Naviaux RK. Alpers-Huttenlocher Syndrome. 2013. Pediatric Neurology 48 (2013) 167e178.

Nuwer MR, Cohen BH, Shepard KM. Practice patterns for intraoperative neurophysiologic monitoring Neurology. 2013 Mar 19;80(12):1156-60.

Blankenberg FG, Kinsman SL, Cohen BH, Goris ML, Spicer KM, Perlman SL, Krane EJ, Kheifets V, Thoolen M, Miller G, Enns GM. Brain uptake of Tc99m-HMPAO correlates with clinical response to the novel redox modulating agent EPI-743 in patients with mitochondrial disease. Mol Genet Metab. 2012 Dec;107(4):690-9.

P.I. Dickson, A.R. Pariser, S.C. Groft, R.W. Ishihara, D.E. McNeil, D. Tagle, D.J. Griebel, S.G. Kaler, J.W. Mink, E.G. Shapiro, K.J. Bjoraker, L. Krivitzky, J.M. Provenzale, A. Gropman, P. Orchard, G. Raymond, B.H. Cohen, R.D. Steiner, S.F. Goldkind, R.M. Nelson, et al. Research Challenges in Central Nervous System Manifestations of Inborn Errors of Metabolism. Molecular Genetics and Metabolism. Mol Genet Metab.Mol Genet Metab. 2011 Mar;102(3):326-38.

Murphy ES, Barnett GH, Vogelbaum MA, Neyman G, Stevens GH, Cohen BH, Elson P, Vassil AD, Suh JH Long-term outcomes of Gamma Knife radiosurgery in patients with vestibular schwannomas. J Neurosurg. 2011 Feb;114(2):432-40. Epub 2010 Jan 22. Erratum in: J Neurosurg. 2011 Feb;114(2):560.

Enns GM, Kinsman SL, Perlman SL, Spicer KM, Abdenur JE, Cohen BH, Amagata A, Barnes A, Kheifets V, Shrader WD, Thoolen M, Blankenberg F, Miller G. Initial experience in the treatment of inherited mitochondrial disease with EPI-743. Mol Genet Metab. 2012 Jan;105(1):91-102. Epub 2011 Oct 21. PubMed PMID: 22115768.

Cohen BH, Saneto RP. Mitochondrial Translation Inhibitors in the Pharmacopeia. Biochimica et Biophysica Acta Gene Regulatory Mechanisms, 2012.

Cohen BH. Coding Issues: Evaluation and Management for Neuro-Oncology Visits. Continuum, 2012.

Agamanolis DP, Katsetos CD, Klonk CJ, Bartkowski HM, Ganapathy S, Staugaitis SM, Kuerbitz SJ, Patton DF, Talaizadeh A, Cohen BH. An unusual form of superficially disseminated glioma in children: report of 3 cases. J Child Neurol. 2012 Jun;27(6):727-33.

Cohen BH, Chinnery P, Copeland, W: POLG-Related Disorders (March 2010) in: GeneReviews at GeneTests: Medical Genetics Information Resource [database online]. Copyright, University of Washington, Seattle, 1997-2010. Available at

Rutkowski S, Cohen B, Finlay J, Luksch R, Ridola V, Valteau-Couanet D, Hara J,Garre ML, Grill J. Medulloblastoma in young children. Pediatr Blood Cancer. 2010 Apr;54(4):635-7.

Cohen BH, Naviaux RK. The clinical diagnosis of POLG disease and other mitochondrial DNA depletion disorders. Methods. 2010 Jun 15. [Epub ahead of print] PubMed PMID: 20558295.

Packer RJ, Jakacki R, Horn M, Rood B, Vezina G, MacDonald T, Fisher MJ, Cohen B. Objective response of multiply recurrent low-grade gliomas to bevacizumab and irinotecan. Pediatr Blood Cancer 2009;52:791-795.

Parkih S, Saneto R, Falk MJ, Anslem I, Cohen BH, Haas R. A modern approach to the treatment of mitochondrial diseases. Current Treatment Options in Neurology 2009, 11:414�430

Messiaen L, Yao S, Brems H, Callens T, Sathienkijkanchai A, Denayer E, Spencer E, Arn P, Babovic-Vuksanovic D, Bay C, Bobele G, Cohen BH, Escobar L, Eunpu D, Grebe T, Greenstein R, Hachen R, Irons M, Kronn D, Lemire E, Leppig K, Lim C, McDonald M, Narayanan V, Pearn A, Pedersen R, Powell B, Shapiro LR, Skidmore D, Tegay D, Thiese H, Zackai EH, Vijzelaar R, Taniguchi K, Ayada T, Okamoto F, Yoshimura A, Parret A, Korf B, Legius E.Clinical and Mutational Spectrum of Neurofibromatosis Type 1�like Syndrome. JAMA. 2009;302(19):2111-2118.

Siddiqui AM. Everman DB. Rogers RC. DuPont BR. Smith BT. Seaver LH. Morales A. Varn M. Cohen B. Traboulsi EI. Microcephaly and congenital grouped pigmentation of the retinal pigment epithelium associated with submicroscopic deletions of 13q33.3-q34 and 11p15.4. Ophthalmic Genetics. 30(3):136-41, 2009.

Parikh S, Cohen BH, Gupta A, Lachhwani DK, Wyllie E, Kotagal P. Metabolic Testing in the Pediatric Epilepsy Unit. Pediatric Neurology 2008;38:191-195.

Haas RH, Parikh S, Falk MH, Saneto RP, Wolf NI, Darin N, Wong L-J, Cohen BH, Naviaux RK. The in-depth evaluation of suspected mitochondrial disease. Molecular Genetics and Metabolism 94: 16-37, 2008.

Wong L-J C, Naviaux RK, Brunetti-Pierri N, Zhang Q, Schmitt ES, Truong C, Milone M, Cohen BH, Wical B, Ganesh J, Basinger AA, Burton BK, Swoboda K, Gilbert DL, Vanderver A, Saneto RP, Maranda B, Arnold G, Abdenur JE, Waters PJ, Copeland WC. Molecular and Clinical Genetics of Mitochondrial Diseases Due to POLG Mutations. Human Mutation (Mutation in Brief) #1020,29:E150-172, 2008.

Weissman JR, Kelley RI, Bauman ML, Cohen BH, Murray KF, et al. (2008) Mitochondrial Disease in Autism Spectrum Disorder Patients: A Cohort Analysis. PLoS ONE 3(11): e3815. doi:10.1371/journal.pone.0003815 Editor: Raphael Schiffmann, National Institutes of Health, United States.

J T Hinson, V Fantin, J Schnberger, N Breivik, G. Siem, B McDonough, P Sharma, I Keogh, R Godinho, F Santos, A Esparza, Y Nicolau, E Selvaag, B H Cohen, C L Hoppel, L Tranebjrg, R D Eavey, J G Seidman and C E Seidman. BCS1L Mutations Cause Bjrnstad Syndrome and Elucidate Novel Tissue Sensitivities to Electron Transport Chain Defects. New England Journal of Medicine 356,(8): 35-45, 2007.

Fattal O, Link J, Quinn K, Cohen BH, Franco K. Psychiatric Comorbidity in 36 Adults with Mitochondrial Cytopathies. CNS Spectr. 2007;12(6):429-438.

Haas RH, Parikh S, Falk MJ, Saneto RP, Wolf NI, Darin N, Cohen BH. Mitochondrial Disease: A Practical Approach for Primary Care Physicians. Pediatrics 120(6):1326-1333, 2007.

Montagna G. Teijido O. Eymard-Pierre E. Muraki K. Cohen B. Loizzo A. Grosso P. Tedeschi G. Palacin M. Boespflug-Tanguy O. Bertini E. Santorelli FM. Estevez R. Vacuolating megalencephalic leukoencephalopathy with subcortical cysts: functional studies of novel variants in MLC1. Human Mutation. 27(3):292, 2006.

Stevens GHJ, Lupica K, Peereboom DM, Suh JH, Cohen BH, Vogelbaum MA, Toms SA, Barnett GH. Levetiracetam (LEV) use in Glioblastoma Multiforme (GBM) patients: a single institution retrospective review of 102 patients with seizures. Neuro-oncology 2006;8(4):304.

Taban M, Cohen BH, Rothner AD, Traboulsi EI. Association of Optic Nerve hypoplasia with Mitochondrial Cytopathies. J Child Neurol 21(11): 956-60, 2006.

Farray D. Ahluwalia MS. Snyder J. Barnett GH. Cohen BH. Suh JH. Peereboom DM. Pre-irradiation 9-amino [20s] camptothecin (9-AC) in patients with newly diagnosed glioblastoma multiforme. Investigational New Drugs 24(3):177-80, 2006.

Farag E. Deboer G. Cohen BH. Niezgoda J. Metabolic acidosis due to propofol infusion.[comment]. Anesthesiology. 102(3):697-8; 2005.

Quan AL, Barnett GH, Lee S-Y, Vogelbaum MA, Toms, SA, Staugaitis SM, Prayson RA, Peereboom DM, Stevens GHJ, Cohen BH, Suh JH. Epidermal growth factor receptor amplification does not have prognostic significance in patients with glioblastoma multiforme. Int. J. Radiation Oncology Biol. Phys. 63: 695-703, 2005.

MA Puchowicz, ME Varnes, BH Cohen, NR Friedman, DS Kerr, CL Hoppel. Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria � case studies. Mitochondrion 4: 337-386, 2004.

A. Gupta, B.H. Cohen, P. Ruggieri, R.J. Packer, and P.C. Phillips. Phase I study of thalidomide for the treatment of plexiform neurofibroma in neurofibromatosis 1. Neurology 60(1):130-132, 2003.

A. A. Herchbergs, L.K. Goyal, J. H. Suh, S. Lee, C. A. Reddy, B. H. Cohen, G. H. Stevens, et al. Propylthiouracil-induced chemical hypothyroidism with high-dose tamoxifen prolongs survival in recurrent high grade glioma: A phase I/II study Anticancer Research 23: 617-626, 2003.

Gliomatosis cerebri: Treatment results with radiotherapy alone. Mohamed A. Elshaikh, Glen HJ Stevens, David M. Peereboom, Bruce H Cohen, Richard A. Prayson, Shih-Yuan Lee, Gene H. Barnett, John H. Suh. Cancer 2002;95:2027-31.

Zervos, K. E. Hunt, H-Q Tong, J. Avallone, J. Morales, N. Friedman, B. H. Cohen, B. Clark, S. Guo, H. Gazda, A. H. Beggs, E. I. Traboulsi. Clinical, Genetic and Histopathologic Findings in Two Siblings with Muscle-Eye-Brain Disease. European Journal of Ophthalmology 12:253-261, 2002.

Wayne Langburt, Bruce H. Cohen, Nadia Akhthar, kelly O'Neill, Jar-Chi Lee. Incidence of concussion in high school football players of Ohio and Pennsylvania. J Child Neurol 2001;16:83-85.

Caroline M. Abramovich, Richard A. Prayson, James T. McMahon, Bruce H. Cohen. Ultrastructural examination of the axillary skin biopsy in the diagnosis of metabolic diseases. Hum Pathol 32;649-655, 2001.

Sarah Rollins, Richard A. Prayson, James T. McMahon, Bruce H. Cohen. Diagnostic yield of muscle biopsy in patients with clinical evidence of mitochondrial cytopathy. Am J. Clin Pathol 116:326-330, 2001.

Regina I. Jakacki, Bruce H. Cohen, Cheryl Jamison, Vince Mathews, Edward Arenson, Darryl C. Longee, Joann Hilden, Al Cornelius, Michael Needle, Doug Heilman, Joel C. Boas, Thomas G Luerssen. Phase II evaluation of interferon-alpha-2A for progressive/recurrent craniopharyngiomas of childhood. Journal of Neurosurgery. 92(2):255-60, 2000.

John H. Suh, Gene H. Barnett, Jason W. Sohn, Patrick A. Kupelian, Bruce H. Cohen. Results of linear accelerator-based stereotactic radiosurgery for recurrent and newly diagnosed acoustic neuromas. Int J Cancer 90:145-151, 2000.

Roger J. Packer, Bruce H. Cohen, Kathleen Coney. Intracranial germ cell tumors. The Oncologist 5:312-320, 2000.

Feliz Rosenow, Prakash Kotagal, Bruce H. Cohen, Carolyn Green, Elaine Wyllie. Multiple sleep latency test and polysomnography in diagnosing Kleine-Levin syndrome and periodic hypersomnia. J Clin Neurophys 17:519-522, 2000.

Janelle L. Park, John H. Suh, Gene H. Barnett, Chandana A. Reddy, David M. Peereboom, Glen H.J. Stevens, Bruce H. Cohen. Survival after stereotactic radiosurgery for recurrent glioblastoma multiforme. Journal of Radiosurgery 2000:3;169-175.

Best Doctor 2007-2008 Best Doctor 2009-2010 Best Doctor 2011-2012 Best Doctor 2013 U.S. News Best Children's Hospitals - Neurology and Neurosurgery 2013-2014 Best Doctors 2014 Best Doctor 2015-2016

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