An atrial septal defect (ASD) is a gap in the wall separating the left and right chambers (atria) of the heart, forcing blood to pass through the hole against the normal direction of flow. Over time, an uncorrected ASD can cause more serious problems, including abnormal heart rhythms, weakened heart muscle, stroke, and in rare cases, high blood pressure in the lungs. ASD is also referred to as a "hole in the heart."
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